Więcej informacji: Benzodiazepiny w Narkopedii [H]yperreala
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jarekjurek pisze:Nie wiem, ale wydaje mi się, że benzo zaniżają kondycję o 80%, przebiegam 200 metrów i się czuję jak po maratonie...
In a study in 1980 in a group of 55 consecutively admitted patients having abused exclusively sedatives or hypnotics, neuropsychological performance was significantly lower and signs of intellectual impairment significantly more often diagnosed than in a matched control group taken from the general population. These results suggested a relationship between abuse of sedatives or hypnotics and cerebral disorder.[59]
A publication has asked in 1981 if lorazepam is more toxic than diazepam.[60]
In a study in 1984, 20 patients having taken long-term benzodiazepines were submitted to brain CT scan examinations. Some scans appeared abnormal. The mean ventricular-brain ratio measured by planimetry was increased over mean values in an age- and sex-matched group of control subjects but was less than that in a group of alcoholics. There was no significant relationship between CT scan appearances and the duration of benzodiazepine therapy. The clinical significance of the findings was unclear.[61]
In 1986, it was presumed that permanent brain damage may result from chronic use of benzodiazepines similar to alcohol-related brain damage.[62]
In 1987, 17 high-dose inpatient abusers of benzodiazepines have anecdotally shown enlarged cerebrospinal fluid spaces with associated brain shrinkage. Brain shrinkage reportedly appeared to be dose dependent with low-dose users having less brain shrinkage than higher-dose users.[63]
However, a CT study in 1987 found no evidence of brain shrinkage in prescribed benzodiazepine users.[64]
In 1989, in a 4- to 6-year follow-up study of 30 inpatient benzodiazepine abusers, Neuropsychological function was found to be permanently affected in some chronic high-dose abusers of benzodiazepines . Brain damage similar to alcoholic brain damage was observed. The CT scan abnormalities showed dilatation of the ventricular system. However, unlike alcoholics, sedative hypnotic abusers showed no evidence of widened cortical sulci. The study concluded that, when cerebral disorder is diagnosed in sedative hypnotic benzodiazepine abusers, it is often permanent.[65]
A CT study in 1993 investigated brain damage in benzodiazepine users and found no overall differences to a healthy control group.[66]
A study in 2000 found that long-term benzodiazepine therapy does not result in brain abnormalities.[67]
Withdrawal from high-dose abuse of nitrazepam anecdotally was alleged in 2001 to have caused severe shock of the whole brain with diffuse slow activity on EEG in one patient after 25 years of abuse. After withdrawal, abnormalities in hypofrontal brain wave patterns persisted beyond the withdrawal syndrome, which suggested to the authors that organic brain damage occurred from chronic high-dose abuse of nitrazepam.[68]
Professor Ashton, a leading expert on benzodiazepines from Newcastle University Institute of Neuroscience, has stated that there is no structural damage from benzodiazepines, and advocates for further research into long-lasting or possibly permanent symptoms of long-term use of benzodiazepines as of 1996.[69] She has stated that she believes that the most likely explanation for lasting symptoms is persisting but slowly resolving functional changes at the GABAA benzodiazepine receptor level. Newer and more detailed brain scanning technologies such as PET scans and MRI scans had as of 2002 to her knowledge never been used to investigate the question of whether benzodiazepines cause functional or structural brain damage.[70]
In 2014 studies have found an association between the use of benzodiazepines and an increased risk of dementia but the exact nature of the relationship is still a matter of debate.[71]
Czyli - dlugotrwale naduzywanie moze doprowadzic do utrzymujacych sie zmian (przynajmniej tak to zrozumialem) ale jest za malo badan ktore by mogly nakreslic gdzie (i czy) jest bezpieczna granica przyjmowania miedzy przyjmowaniem w celach leczniczych (jak doktor przykazal) a dlugotrwalym naduzywaniem.
Nupidron pisze: tylko. Po wyjściu z wody czułem się jakbym ważył z 2x więcej
i potwierdzam do dziś czuje otępienie czy jest szansa aby przywrócić mózg do pełni formy jak to zrobić teraz ?
Rozwiązanie ? Winpocetyna 3x dziennie po 10mg i pamięć jak nówka
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Tona kokainy przechwycona. Gangsterzy wpadli, bo kupili łódź za gotówkę
Z łodzi u wybrzeży Australii skonfiskowano ponad tonę kokainy wartej niemal pół miliarda dolarów amerykańskich. Policja zatrzymała pięć osób.