N-Isopropylcathinone + N-tert-butylcathinone
N-Isopropylcathinone (16) and N-tert-butylcathinone (17) (Figure 4) produced stimulant-characteristic hyperlocomotion in rats at a doses of 7.5 mg/kg and 10 mg/kg, respectively, that were approximately half that seen following administration of methcathinone at 5 mg/kg (Foley and Cozzi, 2003)

I dalej

Learned from early SAR studies was that: i) oxidation of the β-hydroxyl group of (+)cathine to cathinone enhances its stimulant character, ii) cathinone is an amphetamine-like central stimulant with potency nearly comparable to, or greater than, that of amphetamine, iii) the S(−)-isomer of cathinone is more potent than its R(+)enantiomer in various behavioral assays, iv) α-demethylation abolishes cathinone-like behavioral actions up to the doses evaluated, but results in an agent that retains DA-releasing action, v) aryl substitution, at least for those analogs examined, reduces or abolishes amphetamine-like stimulant/stimulus actions, vi) conformational constraint of the side chain of cathinone, as in 2-amino-1-tetralone (12), diminishes stimulant character, vii) N-monomethylation (viz. methcathinone, 13) enhances the potency of cathinone in behavioral assays, viii) S(−)methcathinone is more potent than R(+)methcathinone in behavioral assays, ix) homologation and/or increasing the bulk of the N-methyl group of methcathinone to an ethyl, n-propyl, isopropyl, or tert-butyl group results in retention of stimulant character but in a reduction in potency, and x) N,N-dimethylation of cathinone results in retention of amphetamine-like character, but with a slight decrease in potency. Early studies also provided evidence that cathinone (1) and methcathinone (13) behaved, at least in part, as DA releasing agents.

Źródło
https://www.ncbi.nlm.nih.gov/pmc/articl ... po=22.2826

@surveilled temat zostawiamy tutaj ?

Hm. Interesujące. Wreszcie coś z łańcuchem propanowym od pierścienia... oraz aminą drugorzędową? Ooh la-la!
To może być trochę bardziej serotoninowe od alfa-PPP – a tamto wspominam bardzo miło.

Dział właściwy to "katynon, metedron i inne" – bo tu umieszczamy ketony które nie są walero- (5 węgli), ani maślano- (4 węgle); I które nie mają halogenu; I które nie są wielocykliczne (np. benzodioksol); I nie są pochodną mefedronu (tj 4-metylo); I nie są pirylidynowcami. Proste?