XIV.7. N-metylo pochodna DMAR
1. Symbol związku N-metylo pochodna DMAR
2. Status administracyjny:
Nie występuje w Wykazie środków odurzających oraz w Wykazie substancji
psychotropowych Ustawy z dnia 29 lipca 2005 r. o przeciwdziałaniu narkomanii z
późniejszymi zmianami (2005 r. – 2015 r.).
3. Wzór strukturalny:
4. Nazwa IUPAC: 5-phenyl-2-amino-N-methyl-oxazoline
5. Synonimy: 3-methyl-5-phenyl-oxazolidin-2-ylideneamine
6. Wzór sumaryczny: C10H12N2O
7. Masa molowa: 176.22 g/mol
8. Numer CAS: -
Substancja została po raz pierwszy zidentyfikowana na terenie EU przez
zespół Narodowego Instytutu Leków w Warszawie i zgłoszona do systemu
wczesnego ostrzegania EMCDDA.

2) 5-phenyl-2-amino-N-methyl-oxazoline (N-methyl aminorex derivative)
N-methyl aminorex is a substituted 2-amino-5-phenyl oxazoline, substituted with a methyl group at the 3 position (at the Nitrogen atom) of the oxazoline ring. The presence of a chiral centre within the oxazoline ring (at position 5) gives rise to two enantiomers. Isomeric differentiation has not been reported in the detection. N-methyl aminorex is structurally related to aminorex and 4-methylaminorex (4-MAR) [3], both synthetic stimulants which are listed in Schedule IV and Schedule I, respectively, of the 1971 United Nations Convention on Psychotropic Substances. In particular, it is a positional isomer (same molecular formula and weight) of 4-methylaminorex. There is scarce information available on the N-methyl aminorex derivative. The related compound aminorex was briefly available as an appetite suppressant in Europe during the late 1960s but was withdrawn from the market due to an association with primary pulmonary hypertension [4]. The di-substituted derivative of aminorex – 4-methylaminorex p-methyl derivative (4,4'-DMAR) – was risk assessed by the EMCDDA extended Scientific Committee in September 2014 [5]. N-methyl aminorex was identified in a sample of 0.4 grams of white/beige powder collected by the attorney company from Łódź on the 8th of April 2015. This substance was also analytically confirmed by LC-MS/MS-TOF, GC-MS and NMR at the National Medicines Institute in Warsaw.