Bzdura.

The quantity of grapefruit juice consumed is important to consider, since as little as 250 mL can cause significant inhibition of CYP 3A4.

usual amounts of grapefruit juice have little effect on hepatic CYP 3A4. Large
amounts of grapefruit juice administered under experimental conditions
(e.g., 200 mL double-strength juice three times daily) have been shown to
inhibit hepatic CYP 3A4.

Grapefruit juice: Some grapefruit juice has a (naturally occurring) chemical in it that can interfere with the metabolism of certain drugs by inhibiting an enzyme in your liver called CYP3A4. If a drug is aggressively broken down by this 3A4 enzyme, then grapefruit juice can significantly increase the drug's effect by interfering with its breakdown. Although MDMA can be broken down by this enzyme, it's a minor contributor to the drug's metabolism. As such, inhibiting CYP3A4 would likely have little effect.

Little or no effect is observed when usual amounts of grapefruit juiceare ingested concomitantly with parenterally administered drugs (e.g., i.v.midazolam, nifedipine). Also, no interaction would be expected with theuse of transdermal dosage forms (e.g., estradiol-17 patch) since usualamounts of grapefruit juice have little effect on hepatic CYP 3A4. Largeamounts of grapefruit juice administered under experimental conditions(e.g., 200 mL double-strength juice three times daily) have been shown toinhibit hepatic CYP 3A4.

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selegilina przedluza dzialanie o jakies 2h, zmniejszajac jednoczesnie neurotoksycznasc i kilka innych negatywnych efektow mdma