No ale to wtedy jest juz bomba alkoholowa/marihuanowa/benzosowa, a nie o to mi chodzi.

jacok pisze:

i zostaje parcie na igłę. Nawet jak ledwie widzisz, przysypiasz, to i tak pozostaje ochota, żeby jeszcze trochę dosypać i jeszcze "poprawić". Masakra.

vester pisze:

Omperazol Nie działa w zadnym stopniu na opioidy - nie wzmacnia, nie osłabia - tak samo jak podobny do niego pantoprazol
w ogole oba interreagują z bardzo niewielką ilością leków.
.

wikipedia pisze:

Omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4,[17] and will therefore interact with drugs that depend on these enzymes like most medicines do for their metabolism, such as diazepam and alprazolam. Almost all benzodiazepines are metabolised via the CYP3A4 and CYP2D6 pathway and inhibition of the enzyme will result in a higher AUC (bloodlevels of the drug/compound) which in some cases is going to, or can be lead to coma, death, and hospitalisation due to the interaction since some drugs have a hard time crossing the blood–brain barrier or just cannot be absorbed well enough by the body. Other drugs that are dependant on CYP3A4 for their metabolism are escitalopram, warfarin, oxycodone, tramadol, oxymorphone, etc. (like most, if not all, opioids) which also are metabolised via CYP2D6. (CYP2D6 and CYP3A4 are the main enzymes in the metabolisation of almost all drugs.)[18] The concentrations of these drugs may increase if they are used concomitantly with omeprazole.[19] Clopidogrel (Plavix) is an inactive prodrug that partially depends on CYP2C19 for conversion to its active form; inhibition of CYP2C19 blocks the activation of clopidogrel, thus reducing its effects and potentially increasing the risk of stroke or heart attack in people taking clopidogrel to prevent these events.[20][21] Omeprazole is also a competitive inhibitor of p-glycoprotein, as are other PPIs.[22]

Drugs that depend on an acidic stomach environment (such as ketoconazole or atazanavir) will be poorly absorbed, whereas acid-labile antibiotics (such as erythromycin which is a very strong CYP3A4 inhibitor) will be absorbed to a greater extent than normal due to the more alkaline environment of the stomach.[19]

St. John's wort, an MAO-inhibitor (Hypericum perforatum) and Gingko biloba significantly reduce plasma concentrations of omeprazole through induction of CYP3A4 and CYP2C19