pilleater pisze:

MDMA + iMAO = bedzie źle.

03-05-2002, 01:05
I and other have mixed MAO-A inhibitors (harmine, though moclobemide is also an MAO-A-I) with MDMA before on multiple occasions with no problems. Mixing an MAO-B inhibitor or a nonselective MAOI with MDMA could theoretically lead to a hypertensive crisis and could theoretically be dangerous and maybe even fatal... However, MAO-A inhibitors are (in theory) just going to make the MDMA affect you stronger (and add some psychedelic effects in the case of harmala alkaloids).
It sounds to me like what happened is you took a strong dose of MDMA after taking MAO-A-Is long term and had an unexpectedly strong reaction, leading to an epic freak-out. This certainly could be quite frightening, especially if you are not prepared for how much MAOIs can intensify MDMA. Many people dont realize MDMA is a psychedelic... when combined with MAO-A-I's, it becomes INTENSELY psychedelic. While not physically dangerous, this is far from the happy dance-drug experience many people expect from MDMA, as you found out the hard way.
If you do try mixing MDMA with MAOIs, be aware of these factors, and use low doses of MDMA (less than half what you normally would). Never use MAO-B inhibitors or nonselective MAOIs with MDMA - the only "safe" MAOIs to use with MDMA are MAO-A inhibitors such as harmine, harmaline or moclobemide. Taking MDMA with Deprenyl or any other substances that inhibit MAO-B could be potentially fatal, although no fatalities have been recorded (a few frightening physical reactions have been documented involving Deprenyl though). Taking MAOIs with MDMA is not a recreational experience, its a hardcore psychedelic trip. Don't experiment casually.